Our "new" fridge has R600 refrigerant which to my understanding is "butane". I say "new" because according to the repair guy who has been out multiple times now there are a lot of differences in the equipment needed to make things work correctly with the R600. So, the first fridge bit the dust about 1.5 years ago and no parts were available to fix it, so they replaced the fridge (sounds environmentally friendly right), now the new fridge which was made with "upgraded" parts stopped working, again it was the compressor. Have no fear though, the new compressor is redesigned to work with the R600...
I guess R600 is so safe they just vent it into the atmosphere, no regs requiring them to evacuate it and reuse it. So, while I don't think the R600 is unsafe, I am struggling to see how the transition has been more environmentally friendly. The service guy said he has replaced hundreds, if not more, compressors or whole fridges/freezers since the switch. He said he makes great money doing it. He said not to worry though, we have a new and improved compressor that should work longer than a year this time.
The service guy said they aren't allowed to carry R600 on the trucks due to DOT requiring them to have special permits for those flammable liquids, everything had to ship to our house which delayed fixing it for nearly a week. Super convenient. They also can't do any soldering during the install he said due to the possibility of flammable liquids left in the lines, so the new stuff installed with what looks like some sort of pressfit couplers.
Anyway, thus far, my experience with the R600 has not been favorable.