Just finished a 36X48X14 stud frame shop. I'll tell you what I did. Not saying it's the way to go --just what I did.
8"X30" footing in Eastern Kansas. 5" slab with rebar on 24"OC. Vapor barrier under slab. 2"X6" studs 24"OC. Trusses are 4 foot OC. 26 gauge metal on 5/12 pitch roof. There...