The problem is that in all mechanical refrigeration systems the refrigerant is a "truck" hauling the heat away from the space that you want cooled, without that air moving across an evaporator you will not get cooling. The high velocity systems that are in use today you small ductwork for AC only. I know of now way to eliminate the ductwork other than hotel type heat pumps installed in the outer walls of the space. Bottom line is the heat from the house has to be moved to somewhere it is not objectionable, this is the condenser, always outside.