The cost of operation of any space heating system is mainly determined by the cost of available fuels. Secondly, the cost of operation has to do with the efficiency of conversion - fuel to heat. Finally, what the cost of space heating is determined by the efficiency and the method of distribution of heat.
There is no more efficient way to heat a living space than hydronic heating and where a concrete slab is being poured the clear choice is radiant floor heating. Radiant slabs are all about comfort. With the right heat source, nothing can compare. The fact is, any fuel may be used, be it electricity, natural gas, propane, wood, coal or buffalo chips.
As for response time. Any radiant panel will respond according to the design of the system and the control strategy utilized by the heat source. Forced air may raise the air temperature "quickly" but the determining comfort factor is really the average uniform surface temperature "AUST". Any garage used on a weekly basis can be maintained at a reasonable temperature - say 50°F - by simply turning the stat up 10 degrees the night before would put you in the warm zone.
Properly sizing the heat source and specifying the proper controls makes all the difference.
Remember, radiated spaces are more comfortable than those which are not.