Depends on what you're building . . . . shed or doghouse, then use whatever you have or is cheapest. Either of those will be fine, as failure risk is not an issue.
For structural house framing, then don't take shortcuts. Those nails (even at 3 1/4 inch) are skimpy compared to hand-driven framing nails . . . old school style. A 16 penny nail is about twice the diameter of those air-driven nails (thus lot stronger). Bigger framing nails than 16 penny are often used for main rafters/framing.
OP . . . are you saying that you've OBSERVED house builders purposefully skimping on nails to save a nickel ??