I like using Grizzlies Shop Planner to layout new ideas. It is offline right now for rebuilding but keep an eye on it.
https://www.grizzly.com/user/shop-planner
It has a lot of add ins, shop tools, cars, trucks, even furniture and bathroom fittings that can be used to customize your space.
Also, when you are doing your designs, keep in mind your 30'x50' is only 29'x 49' on the "inside".

Also, as was mentioned, keep your doors at least 4' off the inside walls, especially if you plan a 2 post hoist for that spot. The hoist eats up a lot of space toward the wall and it starts to get pretty narrow with any benches or storage along the wall.
Pay attention to over head doors opening into vehicles on the lift (high lift doors are a good idea).
12' ceilings are a minimum for full height hoist use, scissor trusses and loft trusses are also workable, the loft trusses are cheap sq. footage for storage or a man cave above the shop.

As far as concrete goes you do not have to go crazy with thickness or rebar. BendPak's FAQ site recommends 4" of 3000 psi concrete for their 2 post lifts up to 14K. Of course you can do whatever you feel comfortable with but 4" of 4000psi will do the job.
Mark