Good luck applying more than about 100 ft lbs of torque with a 10" pliers-wrench. It can be done but not without a cheater pipe or literally standing on the handle.
Do you mean a 2" threaded bolt, or a bolt with a 2" hex head? If the former, you're looking at over 2,000 lb ft to tighten it to optimum clamping force. If the latter, that's probably still ~a 1-1/2" threaded bolt which will still require ~1000 lb ft to tighten or loosen.
Now for pipes with flats, I highly recommend the pliers-wrench. I have also used mine successfully on up to 27mm axle nuts on motorcycles to loosen, that have torque specs of about 90 ft lbs. Not ideal or easy to use but it's what I keep in my moto tool kit to save on weight vs a 1/2" socket and breaker bar.
FYI I also have two really big adjustable wrenches, one 18" and one 24". I use the pliers-wrench about 10x as often as either.
Pro for the big adjustable is that you can, in fact, apply more torque with it than a 10" pliers-wrench. Con is that it's huge and unwieldy, and won't fit in many limited-access spaces.
Pro for the pliers-wrench is that you can use it in many more confined areas, and it applies a significant squeezing force on the flats of whatever you're turning which prevents slipping or rounding. It is self-tightening meaning that as long as you're orienting it correctly, once you clamp down on a fastener head, you don't need to continue to squeeze with your hands in order for it to stay tight on the flats while applying torque. Con is... well I guess that it's smaller for the same money vs a big adjustable?
