I have a 24 X 36 garage and I heat it during the Winter. I was planning on putting in central air this Summer, but I decided to just try a window air-conditioner to see how it would work out. By all rights, to cool an area that size I should have a 16,000 btu unit or an 18,000 btu unit. But the garage is built from 2 X 6's so there is R-19 in the walls and there is R-30 in the ceiling. More as a test than anything else, I decided to buy an 8,000 btu unit and see what it would do to cool down the garage.
Well, the 8,000 btu window air-conditioner is not really capable of cooling down the garage to a temperature of 72 degrees. But it does take a lot of moisture out of the air and even on really hot days it does cool the garage down to where you can work out there without much trouble. Unless it is unbearably hot outside, the inside temperature will be in the mid to upper 70's. On super hot days it will hit 80 degrees inside but since the humidity is really low, it feels much cooler than that.
All things considered, even an 8,000 btu air-conditioner can make a pretty big difference in a well insulated area. But if I really want to keep the garage cool, I will need to buy a bigger unit.