I always thought fundraisers like this were just plain exhausting and too roundabout... can't I just write a check and move on with my life?
Anyway, success will depend on the audience the auction attracts; if it's primarily the ladies, which is usually the case, then your wife is correct. I mean, sure, there are some ladies who would be delighted with a new Wilton vise, but they are not in the majority.
Even if they make an effort to attract men to bid, like the "man room" above, you'd still need to go much more mainstream. Remember, many of these items would actually be purchased by women as gifts for men, so try to figure out the kind of stuff women think men want.
Bundles and baskets always work VERY well. Woodworker's supplies and tools, sportsball stuff, tailgating/grilling supplies, oil change tools, car detailing, or even computer gaming, etc. could do well. Chuck it into a grotty old basket from Goodwill, decorate it with some leftover Easter and Christmas stuff, and you're off to the races.