I completed my 30x50 Mueller red-iron building last month. Depending on your county/local requirements you may be required to have an engineered foundation plan, which is often pretty elaborate and expensive.
I didn't need an engineered plan where I live, but used a concrete contractor that deals with commercial buildings and has experience with red iron foundation requirements. A lot of residential outfits that deal primarily with pole buildings and stick built will tell you to pour a simple 1' wide footer down to frost depth (to meet your county requirements) and wedge anchor the columns into the slab. They don't realize that these buildings have special requirements due to the uplift potential (they're lightweight and only held down by a few columns), and assume they just need the foundation/footing to bear weight, which is not true.
I ended up spending basically the same in concrete as I did the building. ($17K concrete plus $17K building). I did 2' wide perimeter footing all the way around to about 30" deep, plus 5" slab. That price is just the basic building + concrete, I had extra cost for insulation, and did the erection myself.
In hindsight I should have gone with a pole barn. It would have shortened lead time dramatically (there was a cement shortage here when I built mine and had to wait months). In the area I live, nobody builds red-iron buildings (for home use), so finding a concrete contractor that knew something about red-iron AND would take on a "smaller" job like this was a real challenge.
Depending on where you live and how popular red-iron buildings are, your mileage may vary.