My shop is half and half, so i feel your pain. Never enough space. Here's a short description. Maybe it'll give you a few ideas as to what NOT to do.

For the record, my daily driver stays in the driveway and I'm not married, so there's no point of contention there.
I've got a dual purpose workbench on one side that I currently use for both automotive stuff and woodworking projects. It holds my grinder, drill press, 2 vises, etc. My toolbox, floor jack, jack stands etc. sit beside it. I store all my power tools below the bench and alternate my POS table saw and my compound miter saw on a b&d workmate in the middle of the "shop" bay. With this setup, i've still got a lot of open floor space to work around things. However, I'm planning on adding a few larger power tools (either a cabinet or a hybrid table saw, planer, jointer, etc. ) and building a dedicated woodworking bench (a roubo design, for those familiar with such). This will likely kill my "set up a card table and have Christmas dinner in the garage" space, but i should be able to get by.
My '62 galaxie has the other side of the shop. Anybody who's familiar with a galaxie knows that wherever you put it, that's all you're putting there. I've got enough room to work around it but it's tight.
Never enough space!! I'd love to have a dedicated shop for both woodworking and auto work (and a separate building for a music studio while I'm sitting here daydreaming!

) but that will have to wait.
Best of luck in your endeavor. I know a lot of guys who believe in putting everything on wheels. This works. Also, make sure all of your surfaces (benches, router tables, etc.) are the same height if possible. This lets you work longer boards using the rest of your shop for an outfeed table.