You need to figure out how much air you want to exhaust. Think of this as how fast to you want to recycle the air in your building. keep in mind that what goes out must come back in. If you start exhausting to much, then you will need an inlet air supply.
Overhead garage doors are a great example. Depending on exhaust fan size, you have a huge inlet. What if you do not want the doors open? Also keep in mind that the airflow inside of a building will be between the inlet and outlet. So if they are centered in the room, exhausting the air out of a corner may still need a fan to get it circulating.
You need to decide what the use of an exhaust fan would be. Design it into the building for the way you want to use it. If it just to cool it off in the hot summer, OK. If it is to vent a task that you are doing, then do it right.
I know when I got a home occupaion permit to work on cars at home for a business, the city required one that moved 1.5 CF of air, for every square foot of floor space. I am in Iowa and have a very insulated garage with force air heat. They did not require an inlet. To this day I do not turn it on if the resnor is running in the corner. The chimney does work very well for a fresh air vent, if doors are not open.