It would depend.
If your hot water heater tank is rated for your well or street pressure or more BUT your heating system is designed for lower pressure, you may be overstressing your "heat emitters".
I use a DHW and heat emitter boiler with DHW priority (I set this default).
I have in-floor PEX pipes as well as steel baseboard radiators.
I have a double problem to lower the heated and treated water being fed into my radiators (lower pressure and higher heat (temp) and my PEX system requires lowered temps and can handle more pressure than my radiators.
I have a dedicated water temp mixer to manage the PEX side's output temperature of 110 degrees F. The PEX side's pressure is regulated by the pumping system as well as what I set my expansion tank's pressure at.
Yes, I am aware of my steel baseboard radiators being designed to handle larger pressure but I rely on the set pressure of my expansion tank to maintain pressure as well as absorb over pressure from the boil when DHW or heat is demanded.
The focus is now on my boiler and its pressure relief valve which is set for 30 PSI and ? temperature.
In conclusion, I have a water makeup feeder system that I set for 15 PSI and set my pressure on the expansion tank at 12 pounds.
I also have an expansion tank set for 65 pounds on the external DHW tank as my street water pressure is at 80PSI but I also have a who house pressure reducer that lowers the pressure to 65PSI.