To contribute to this thread, I went with round snap- together duct for my shop system, as I used it after a flood situation once, and was familiar with it. Easy to obtain and assemble, and fairly inexpensive from Noland Company. My unit is a 2.5 ton heat pump with 1000 to 1100 cfm IIRC. It was used, and had 14 inch takeoffs, so I went with that, stepping down later to 12, 10, and finally 8", in succession. There are ten 6" short runs of flex outward and down from the main trunk, which is run through the shop attic, dumping downward into the room. Four are in the 14" section, and two each in the other sections, for a total of ten 4x 10 outlets The trunk will have sealing mastic, along with vapor barrier duct insulation wrap. I have a 2 foot long return duct from the room straight out the wall to the unit. Flex connectors were also used to reduce noise and vibrations from the unit into the metal of the ductwork. Am I anywhere close to having a decent distribution system here? I will try to post up pics later when I can.