Only reason I even considered a 2-stage is it would be nice to have a compressor that maxes out around 165psi. I have a Ford F550 and GMC 70 medium duty, both of which have tires running 110psi. While the Ford isn't as bad to get to 110psi, the GMC can be rather time consuming. That being said, it isn't a make or break kind of deal (and its not like I'm having to pump up tires weekly).
This would actually be my 2nd large compressor, my other is an 80gal IR that offers a a little more CFM (but also maxes out at 135psi). I have a 2nd shop, and I've wired it up for a 240v compressor. I'd initially planned on using a smaller 30gal horizontal Craftsman 240v unit, but this one offers a little more CFM.