When you are referring to "mixing valve" are referring to the automatic versions, or just a gate valve that you can use to adjust your temps of your primary and secondary loops?
My hi temp boiler uses a manual gate valve and it seems to work just fine. The water circulating around the boiler stays at or near 140*f and my loop or zone to my floor is kept at or near 105*f.
I would like to know more about the boiler. Is this a hi temperature boiler? If so you need to keep the temps in and out of the boiler elevated to keep any condensation issues in check.