I agree with the comments made above, get rid of the overhead door, get more insulation, and go with a refrigeration system rather than an air-conditioning system.
I would also recommend spray foam insulation rather than regular fiberglass insulation. You get more “R” value per inch from the spray foam than you do from regular fiberglass insulation. For example, with the regular pink fiberglass insulation you get R-13 in a 2X4 wall and you get R-19 in a 2X6 wall. But if you have 2X4 walls with spray foam you would get R-6 per inch so if you fill the entire cavity with spray foam you should get about R-21. If you have 2X6 ceiling with fiberglass you get R-19 and with spray foam filling the entire cavity you would get about R-33. While the initial cost would be much higher to do the spray foam, in the long term it would make a big difference in the monthly cost to heat/cool the garage. I guess it all boils down to what you prefer, a larger initial cost followed by a lower monthly cost to operate, or a lower initial cost followed by a higher monthly operating cost.