It pays to plan lighting carefully.
The first question to answer is how much light do you want? foot candles or lumens/sq. ft do you want.
This page
http://www.engineeringtoolbox.com/light-level-rooms-d_708.html does a good job of explaining lighting levels and provides examples of common lighting levels.
The next thing you do is you use a lighting calculator to figure out how many bulbs it will take to achieve this lighting level in an ideal world. Here is a lighting calculator
http://www.gelighting.com/LightingW...sistant-toolkit/lighting-layout-estimator.jsp
Next you figure out how non-ideal your shop is. The ceiling of your shop is not a perfect reflector, shelving along the walls will absorb light, your walls are not mirrors and the darker the color the more light they will absorb, and without fixtures specifically made to focus light downward (look a "high bay" fixtures to get an idea of this) the higher the lights are mounted the more light will be lost to lighting the walls as opposed to the floor (notice that most lighting calculators assume the only thing being lit is the floor).
Finally after you've figured out how many bulbs it will take to light to the desired level factoring in how non-ideal your workship is, you need to figure out what type and how many fixtures you need to ensure that light is evenly distributed throughout your shop. While fixtures which hold more bulbs may save on wiring costs, they may not be as effective and avoiding shadows and evenly distributing lights.
In my case, in my 48x24x14 workshop I wanted 100 foot candles. I calculated and designed for 200 foot candles to compensate for how non-ideal my workshop is and ended up with 88 4' T8 daylight spectrum bulbs in 44 fixtures mounted in 4 rows of 11 fixtures. My total cost for the bulbs and fixtures was about $1800 (Menards on sale was the lowest cost source I found). This is how it ended up.
Notice that due to the overhangs, I ended up buying more lights to light the overhung work bench areas and the area under the pallet racking.
FWIW