Lighting is considered a continuous load under the NEC, and continuous loads cannot exceed 80% of a circuit or device's rated capacity. Thus a 15 amp circuit is limited to 12 amps max load and a 20 amp circuit is limited to 16 amps in this situation (and a good rule to follow in any situation, not just continuous loads).
Look at your lighting devices, the ID tags on them will have the total load of the fixture or device, add these up and as long as they do not exceed 12 amps or 16 amps, depending on the circuit, you are OK.
Random Guy makes a good point of separating the circuits however, and that is a good policy to follow also.
Charles