In the world of construction you can do anything if you have the $ and time. You can always tear it out.
In all seriousness, open the wall to the left of the hvac duct to see what’s there. If nothing, then confirm no other conflicts and figure out how to move duct one stud bay without affecting air flow to above. I’m thinking a bay shift is not favorable above.
The header span is now wider (larger header likely needed) but you can post this down to steel below.