Thinset (or equal) is a great product, sure beats portland cement for adhesion. Follow the instructions for added water and the consistancy of the mixed product
You may neede to added water to maintain the correct consistancy as you work.
If the back of the tile is not fully skimmed coat, possible the troweled thinset on the floor will not stick to the tile, or fully adhere, which causes a possible hollow or weak point in the tile. Do not allow hollow spots.
Make sure you have spare tiles for the future, in case a tile(s) cracks years down the line!!!
As Duneslider recommends, pre mix grout, usually they are fortified with a strengthener
Likely you will take more than a day. When finished for the day carefully scrape ANY thinset from the floor right to the edge of the install tile.
As you set the tiles, remove any thinset which oozes up between the tiles. once thinset dries it is hard to remove, and likely will not match the tile grout color.
Do you have knee pads, Home Depot/lowes have them. Gloves are needed if the alkaline in the thinset or grout starts messing with your hands.
If you have a bad back, do you have a back support? It not so much the lifting as leaning over for long periods.
A slightly damp floor/tiles, NOT WET helps thinset stick. This is a bit tricky, wet is not good.
Know when to quit for day before you over do it.