I'd NEVEr throw away a Purdy brush. I also have one or two good bristle brushes my dad bought from Sears in the 60's, and they're still good. I've NOT had good luck with that brush cleaner stuff. Best suggestion I've heard here so far is rlitman's soak the brush in the appropriate thinner BEFORE putting the brush into the paint. Add to that, don't dip the brush in the paint up to the ferrule. Keep it away at least 1/2" to 3/4". Last, after washing it REALLY good, combing with a brush comb AND palm spinning it, put a final clean thinner in it, shape it by putting it back in its wrapper or in a paper towel rolled into its correct shape. Lay it or hang it, don't stand it up and bend the bristles out of shape.