It seems that we have tapers and dopers here. There is a place for each and neither will work in every situation. I've seen knotheads that use tape on flair fittings. There are different tapes and dopes for for different applications. Gas fittings require a different sealant than water fittings. There are a few dozen different dopes out there, and some for good reason. If you consider that Teflon is not a sealant but a lubricant for threads that are tapered then you answer may become apparent. Study tapered pipe threads, learn how they do not seal at the root/peak interface and the role that a sealant or lubricant plays.
There is also the issue of what you are fitting together. Some air system in the garage with home depot fittings or some hi-tech equipment with Swagelock fittings where no leakage is permitted, and assembled fittings are gauged to make sure they are assembled to specifications.
This is another one of those subjects where so many inputs from so many from different people of varied backgrounds and skills completely render the answers useless. OP if you get specific about what fittings you are using, what fluid are you sealing against, fitting materials, and any other variables that may apply then you can get an answer. This question is akin to asking whether air or water is more important? I would have to ask, are you drowning or stranded in the desert?
lg
no neat sig line