its different for everybody
and for the first few years you will be moving it all around to get comfortable
after 3 years mine still isnt perfect, but im getting closer
top drawer - scantool, scope, powerprobe, multi meter and full set of metric and inch 3/8 sockets
second drawer - the majority of my wrenchs
third drawer- electrical, crimpers, jumpers, relays, test leads you name it
fourth - normal screwdrivers, hose picks, chisels, files, special pry bars, gauges
fifth - taps, dies, rethreaders, 1/2 to 3/8 extension, air hammer bits
sixth - sockets, torque wrenches, and more sockets, die grinders
seventh - everything else, 3/4 sockets, snapon ball joint press, pullers, 4 1/2 grinder, mapp torch, everything big and beefy
but honestly i do most of my work out of a cart with full drawers, and really only out of the top 3 drawers
top has 1/4 stuff, picks, upholstery tools
second drawer has 1/2 impact, torque sticks, commonly used 1/2 sockets, gear wrenches, tire gauge and blow guns
3rd has 3/8 sockets and tools