When it comes to drive tools, the leading letter indicates drive size (with the exception of a G preceding any of the following - G indicates non-chromed industrial finish):
T = 1/4" drive
F = 3/8" drive
S = 1/2" drive
Past that, then there is:
L = long handle
LL = extra-long handle
H = some kind of plastic handle (comfort grip or hard handle)
F = Flex
X = Locking Flex
S = Speeder Handle (discontinued after the FSLF936)
C = Compact
B = Bent Handle
The 72 in 1/4" drive indicates 72 teeth, the 80 in 3/8" or 1/2" is 80 teeth.
Earlier models had a 32 or 36, indicating that number of teeth (i.e. S832 or S936).
A trailing letter after the number (so far, I've only seen A) indicates a revision.
There's undoubtedly a lot more...