I think that's just an optical illusion. The screw looks to be centered if you look at the top of the clamp.As the others said, Vee blocks. I see a seam in the rail
I’ve never seen the clamp with the off center screw.
V Blocks are used for clamping round items typically.Vee block, but I’m not near smart enough to tell you what a machinist would use them for. But I know that ammo makers and custom gunsmiths use them for accuracy and press testing in controlled environments.