The best way to reduce spatter is to have your settings dialed in correctly. Most of the problems I see are from either not having enough voltage or having too much wire speed. Both have the effect of changing the arc length and the heat input to the weld. Generally, I try to weld in spray-arc when possible, but that's difficult to do with thinner materials.
Also, make sure the surfaces you are welding are clean, dirty material increases spatter. If you are welding outdoors, you may be getting the shielding gas carried away by a breeze. Are you pushing or pulling the puddle? Pushing the weld puddle will generate more spatter than a neutral/drag position of the torch. Are you using pure CO2, or a mix like C25? Pure CO2 will generate more spatter than an Argon mix.
As far as using something like Pam, I know lots of people that use it, though I'm not really a fan. I would stay away from using WD-40 as an anti-spatter, the introduction of hydrocarbons into the weld pool isn't a good thing, and who knows what kind of fumes are released at welding temperatures.