You definitely want to run 100% co2 for steel. It makes more splatter, but has far more penetration than c25. You didn't say what mig you have, etc.. My mig welder is an inverter based unit, and it was programmed for 100% co2. It actually makes less splatter on 100% co2 than a transformer based machine on c25.
I have 3 20lb co2 tanks currently. 2 are for mig welding, and 1 for my powertank setup (xp400 reg) I use for running my impact, airing tires, stuff like that. I sometimes keep one in my truck even though I have an OBA setup that does 5+Cfm@90psi, but it mostly lives in my landcruiser.
I could easily have bought larger tanks for the price of the 20pounders. They're easy to carry (integrated handle / some valve protection with reg installed), small, and light. I think the rule of thumb for mig is you can do 15' of 1/4" plate single pass on 1 pound of co2, or 7' of 1/2".