If you do this, I recommend using a fine toothed blade, as fine as you can buy. A low-tooth (large gap) blade will instantly shear that plastic.
At the same time, be aware that some plastic, regardless, will shatter. Have your PPE on, as you don't want this stuff to smack you. I've had something shatter on a miter saw, had sharp large pieces flying everywhere, some hit the the wall, some hit me, scared the **** out of me, etc. Be aware when something like this shatters, your body has the natural instinct to jerk up slightly, or also try to grip/push down on the piece, so be very careful not to jerk your hand into the blade and severely injure yourself.
While you can do this safely, just be aware. You have other options, such as an oscillating tool, a dremel, a 4-1/2" angle grinder, etc.