FAA Advisory Circular 43.13.2B
http://www.faa.gov/documentLibrary/media/Advisory_Circular/AC 43.13-2B.pdf provides some guidance in Chapter 1 on acceptable methods, techniques, and practices for aircraft alterations.
Outlined is a process;
-determining load factors
-estimating the resulting loads
-distributing the loads over the aircraft structure
-determining the material, size, and shape of the part
-calculate the resulting stresses in the part
-compare these stresses with the maximum allowable for the material used
-resize the part as necessary
Then it discusses the types of loads and stresses, static loads, structural sizing and analysis, static tests, materials and workmanship, material strength properties and design values, fasteners, protection of structure, accessibility, affects on weight and balance, affects on safe operation, controls and indicators, and placarding. Finally it presents example worksheets for determining static test loads.
Might be worth looking it over for guidance. Even if your aircraft is experimental, these are the types of guidelines that an examiner would be using to evaluate the airframe mods. Either before or after an incident.