I had similar requirements when I built my shop. It is small though, 30x32x12.5. Well insulated and sealed, 2"xps under the slab, 6"+ slab thickness. I could have put any system in that I wanted as I was in the trade. I decided on a natural gas fired radiant tube. For what it cost to install and no worries about what I might decide to do in the shop in the future made the decision easy. I am considering getting a bigger lathe and mill so the option to bolt them down is important. I keep the temp at 65-68 all winter as I like to jump back onto a project when I have time. That could mean every evening or maybe once or twice a week. I also really don't like cold tools. A forced air gas heater will heat the space quickly, but not the tools in the tool box. Mini splits might be good but I'm lazy and hate dealing with dirty greasy evap coils and air filters, there'sa good chance maintenance would suffer. I figured keeping the place warm 24/7, having the option to drill wherever I wanted, and no need to deal with dirty air filters left me with only one choice. I'm completely pleased with the tube heat. Serviced once a year and there's been no issue in the past 6 years. Combustion air is ducted outside, which makes the unit really quiet. It does have the odd expansion creak when heating, but since it is on maintaining a steady temp it doesn't run all that much.
Everything has it's pros and cons, you have to decide what suits your needs (and possible future needs) best. Good luck with your decision.
Everything has it's pros and cons, you have to decide what suits your needs (and possible future needs) best. Good luck with your decision.

