I mean come on its a tube in the concrete. Ok so what does it take besides that?
fittings, pumps, controls, manifolds, heating source, pressure tank, drains, cut offs, air eliminator, etc.
Do you have to insulate between the concrete and the stone?
Yes, if you don't want to waste money heating the ground and you need a vapor barrier under the foam insulation.
What does it cost in material to do say 1,000 square feeet so it's easier to calculate if people have less or more space.
less than $2,000 for 1 pump and all the other stuff except the heating source. Half of that cost is 2" foam insulation. Heating source will vary greatly in price with type.
What do you have to do to maintain it?
Perform required maintenance on heating source and maintain water and pressure levels.
Does the concrete have to be deeper?
No
Do you have to keep it away from walls?
Pex should be spaced 12" away from exterior wall and the first two runs of pex closest to the wall should be spaced 6" apart. All the other pex runs would most likely be spaced 12" apart but heating design requirements will determine that.
Also how do you keep from hitting it later if you drill holes in the concrete?
Do accurate measurements on the layout and keep photographs and all layout drawings. You have to design the layout with walls, lifts, etc. all taken into consideration.