Step drills are designed/best used for thin materials like sheet metal. They won't grab as you break through & self feed. They'll produce a cleaner/rounder hole than using a standard twist drill in thin materials.
In machining, straight flute taps are generally stronger than spiral flute taps. Spiral flute reamers can be used in holes with an interrupted cut like a hole with a keyway where as straight flute reamers are only recommended for non-interupted cut. Sprial flutes cost more to manufacture, for that reason I only own straight flue reamers. I do own some spiral fltue taps but not many (great for blind holes).
Maybe spiral flute step bits might have an advantage over straight but none that I can think of, for my uses anyway. Perhaps a spiral flute step bit might have a tendency to stay centered better than a straight flute. Better chip evacuation is not a concern for me cause I only use step drills for thin materials as recommmended, not a whole lof chip load anyway.
At my work & for what I do/work on, I use step drills much more often than twist drills. I use straight flutes though.