Any pointers laying such large tiles with such a small gap?
There are a lot of pointers and guidelines out there for large tiles and small gaps. A lippage/leveling system and hard spacers (not the squishy rubber ones) are certainly helpful (multiple work at different price points and levels of "goodness"). Flat walls can be critical.
There are also guidelines for the minimum suggested gap size relative to the variation in tile sizes. Rectified tiles help, but all tiles have some variability in length/width. Going from memory, I think the gap is supposed to be at least 3x the variation in tile size (you can stack 5-10 tiles on their side and see how much variation there is). Smaller gaps are possible, but you'll notice the variation.
The bow of the tiles also can be a factor. Most tiles have some bow, especially as they get bigger. You can put the tile on its face and see if it spins. A 50% offset in tiles from row to row will maximize the problem, with the low spots on one row right next to the high spots on the next row, creating lippage. Potentially ugly on a wall, and potentially a trip hazard on a floor. Again, bigger gaps between tiles helps hide this. Also, the placement of a ceiling light for a wall can hide or accentuate the shadows created by lippage. For big tiles, most people recommend a 1/3 offset between rows as a maximum.
That all being said, 1/16" gaps would make me a little nervous unless the tiles are VERY flat and uniform. And I'd definitely want rectified. I've used 3/32" gaps for tiles of similar size, and think that can look really nice (still with uniform/flat/rectified tiles).
I'm relatively new here, so I don't know if I can link to other forums, but there are some tiling-specific forums that can be very helpful for info like this.
Good luck!
Tyler