I use my setup pretty much the opposite of you Matt. My CO2 tanks are my primary source of airing up tires, which is why I carry two vs. just one. I cannot get through a full rally/gathering (six days) of wheeling on only one tank. I can get 4+ full air ups (16-18 tires) on these 37's from trail pressure (12 PSI) back to street pressure (28 PSI).
I've had multiple air setups over the past 11 years of owning this Jeep now. Prior to this Jeep I just used a portable Viair setup in a canvas bag in the back of the Jeep that I used for airing up. It worked great but I wanted something more permanently mounted when I got the JK. With this Jeep I went from the portable to a mounted, to a complete dual compressor with air tank setup and then back to a single mounted in the rear cargo area and NONE of them impressed me and ALL but the portable setups had compressors fail due to heat. About 5 years ago I had given up on Viair and bought the dual ARB and mounted it under the passenger's seat. This setup worked flawlessly but still a bit slower than I liked. I was always one of the last to be aired up, usually because I was either tail-gunning and getting to the air-up spot last OR if I was leading I would check on everyone in the group as they rolled in to ensure everything was ok and I was still the last one aired-up.
When I went to the 37's I said enough is enough and I wasn't going to be holding others up or leaving 20-minutes after everyone else so I went with the dual 10 pound Powertanks and haven't looked back. I kept the dual ARB under the passenger's seat as redundancy. You know the old saying, "two is one and one is none." I then figured out it was a great way of thawing out the frozen coiled air hose which would allow me to quickly put everything away in its proper place without having to wait until back at camp when the hose thawed out.
It is also not uncommon to air down and back up more than once a day depending on the trails we run and distance between them. If only a few miles to about 10 miles I generally won't air up and just take it slow. However, more time than not it is much further than that, especially when we wheel in South Dakota or Ouray areas so having a quick way of airing down and back up is nice and the Powertank fulfills that need. Plus it is relatively inexpensive to refill once we arrive back home.
As for popping beads I have never lost one on the trail so I can't justify beadlocks nor want them but 12 PSI is the lowest I air down to. Been on the trail with a few friends who have lost a bead here and there and nearly every time I could tell when it was going to happen by the way or angle that they attacked the obstacle. Maybe if I had lost beads a few times I would feel differently but I have a completely different take on beadlocks. Plus with our local club most of the mall crawlers think they HAVE to have beadlocks otherwise they're not real Jeepers.

My wife is convinced part of my stubbornness is just to prove them wrong. She may be on to something.
As for air pressures, I pretty much air down to 12 PSI when doing most trails. IF only fire roads and just want to take the harshness out of the ride I may stop around 15~ish PSI but I always air down nowadays. It's not worth beating the **** out of the Jeep or the passengers by running at street pressure if even for a short trail. Too quick and too easy to air down not to.